Garcinia Mangostana L.Pericarp Gel as a Local Drug Delivery in Treatment of Chronic Periodontitis

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

A single-center, randomized controlled clinical trial was done to assess the periodontal status of the individuals and the presence of red complex microorganisms (RCM) such as Treponema denticola, Porphyromonas.gingivalis and Tannerella.forsythia in the subgingival tissues of periodontal pockets at baseline followed by the application of mangostana gel as an adjunct to scaling and root planing. The periodontal parameters and RCM were again assessed at 3rd month and compared with the placebo group.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Meenakshi Ammal Dental College and Hospital
• Treatments: Anti-Inflammatory Agents

Criteria

Inclusion Criteria:

• Age: 30 to 65 years

• Systemically healthy subjects with chronic periodontitis

Exclusion Criteria:

• aggressive periodontitis,

• systemic disorders,

• known or suspected allergy to the MGA/placebo group,

• pregnant and lactating females,

• long term steroid medication,

• smokers,

• alcoholics,

• immunocompromised individuals and

• those with history of antibiotic or periodontal therapy in preceding 6 months