Gait Patterns After Intraarticular Treatment of Patients With Osteoarthritis of the Knee

• Status: Completed
• Trial end date: 2005-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study was to analyse the difference of the functional and clinical outcome after intraarticular treatment of patients with osteoarthritis of the knee with a single injection of hyaluronan (HA) or Triamcinolone (TA) with respect to the quality of life during the study period.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Philipps University Marburg Medical Center
• Collaborator: University Hospital Muenster
• Treatments: Hyaluronic Acid; Triamcinolone; Triamcinolone Acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide

Criteria

Inclusion Criteria:

• men and women between 35 and 80 years of age

• radiographically verified degenerative osteoarthritis of the knee (grade II or III according to the Kellgren and Lawrence classification)

• pain of at least 40 mm on a 100 mm visual analogue scale (VAS) at initial examination

• persisting pain for at least 6 months

• Lequesne-Score of at least 10 points

• good physical and mental status

• good compliance and agreement to participate in this study

Exclusion Criteria:

• non-degeneratively induced osteoarthritis

• rheumatoid arthritis

• ligamentous instability or complete resection of the meniscus

• Sudeck´s disease

• operations of the affected knee within the last three months

• varus or valgus deformity of more than 15 degrees

• patellofemoral arthritis

• intraarticular therapy of the affected joint within the last 6 months with hyaluronan and three months with glucocorticoids

• severe systemic diseases (tumor, exacerbated diabetes mellitus, hyperthyroidism)

• anti-thrombotic medication or regular medication with NSAID/psychiatric pharmaceuticals

• infectious diseases

• alcohol abuse

• drugs

• psychiatric diseases or suicidal tendencies

• involvement in another study

• non-compliance

• acute hemarthrosis or joint effusion

• allergic predisposition

• skin infections or skin diseases around the knee