Gabapentin vs Chlordiazepoxide for Ambulatory Alcohol Withdrawal
Status:
Completed
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
A randomized, double-blind controlled trial comparing treatment outcomes between
chlordiazepoxide, or gabapentin to treat alcohol withdrawal syndrome in alcohol dependent
veteran subjects. The objective of this trial is to compare the safety and effectiveness of
these two medications. Intervention is a fixed dose taper of chlordiazepoxide, or gabapentin
over 6 days. Subjects will be evaluated for 7-10 days to monitor alcohol abstinence,
withdrawal severity scores, adverse events including ataxia, sedation, cognitive function and
alcohol craving.