Gabapentin for Pain Management During Dilation and Evacuation
Status:
Completed
Trial end date:
2020-05-20
Target enrollment:
Participant gender:
Summary
Justification. Pain control is still an issue for women undergoing second trimester abortion
procedures. The investigators propose a randomized controlled double-blinded trial evaluating
the use of adjunct gabapentin versus placebo in addition to moderate sedation during D&E. The
investigators hypothesize that 600 mg oral gabapentin administered pre-operatively at the
time of cervical preparation initiation will improve intra-operative pain control. The
investigators also hypothesize that it will improve pre- and post-operative pain, anxiety,
nausea, vomiting, and overall satisfaction with pain management during D&E.
To test the hypotheses the investigators plan to enroll 130 participants who will be
randomized 1 to 1 to receive either 600 mg gabapentin or placebo at the initiation of
cervical preparation.