Overview

Gabapentin and Pressor Response to Intubation

Status:
NOT_YET_RECRUITING
Trial end date:
2025-07-16
Target enrollment:
Participant gender:
Summary
This study evaluates the effectiveness of oral gabapentin in reducing the pressor response (increased MAP, HR, and BP) during laryngoscopic intubation. It is a prospective, double-blind randomized controlled trial involving 144 patients undergoing elective surgery. Gabapentin 300 mg or placebo will be administered preoperatively, with hemodynamic parameters monitored before and after intubation. The study aims to determine if gabapentin attenuates the sympathetic stress response compared to placebo.
Phase:
PHASE1
Details
Lead Sponsor:
Liaquat National Hospital & Medical College
Treatments:
Gabapentin