Gabapentin Premedication and Adenotonsillectomy in Pediatric Patients
Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
The frequent incidence of postoperative vomiting and severe pain in children undergoing
adenotonsillectomy, may delay postoperative oral intake and increase the risk of dehydration.
Postoperative nausea and vomiting (PONV) is of multi-factorial origin in this group of
patients, with a reported incidence ranging from 23% to 73%.
There is growing evidence that the perioperative administration of gabapentinin in adults is
beneficial for preoperative anxiolysis, postoperative analgesia, reduction of postoperative
nausea and vomiting, and delirium.
Only few studies in literature explored the analgesic effects of preoperative gabapentin as
premedication in pediatric population. However, the antiemetic effect of gabapentin in
pediatric patients was not systematically investigated before.