Overview

GLP-1 Infusion and Long-Time Fasting

Status:
Completed
Trial end date:
2007-05-01
Target enrollment:
Participant gender:
Summary
GLP-1 is an incretin hormone that simulates insulin secretion and inhibits glucagon secretion in a glucose dependent way. Below normal plasma glucose levels the effects of GLP-1 stop and the risk of hypoglycemia is small. However no results exits on the effects pharmacologically relevant doses of GLP-1 during long-time fasting. There seems to be a risk of hypoglycemia in healthy people after a fasting period when a glucose load is administered. The risk of hypoglycemia when GLP-1 is administered will be evaluated during these two conditions.
Phase:
N/A
Details
Lead Sponsor:
University of Aarhus
Treatments:
Glucagon
Glucagon-Like Peptide 1