GHB Withdrawal Symptoms and Effectiveness of Treatment With Lorazepam Versus Pentobarbital - 1
Status:
Withdrawn
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
Gamma hydroxybutyrate (GHB) is a powerful central nervous system depressant. The number of
individuals seeking treatment for GHB abuse has been steadily increasing in the United
States. Currently, lorazepam and pentobarbital are two medications used to treat individuals
who experience GHB-withdrawal symptoms. The purpose of this study is to describe the signs
and symptoms of GHB withdrawal and to identify predictors of withdrawal severity. The study
will also evaluate the safety and effectiveness of treatment with lorazepam versus
pentobarbital for GHB detoxification.