G-CSF and Autologous Cord Blood Infusion in Cerebral Palsy
Status:
Unknown status
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
This study is performed to reveal the safety and feasibility of combination therapy with
autologous cord blood mononuclear cells (CB) and G-CSF as well as repeated administration of
G-CSF for children with cerebral palsy. The evaluation tools are as follows: (1)
Developmental tests (DDST, PEDI, GMFM, GMFCS, MACS, QUEST), (2) Neurocognitive function test
(WPPSI-IV), (3) Brain MRI-DTI, (4) Peripheral blood CD34+ cell counts, (5) Neurotrophic
factors/anti-inflammatory cytokines.