Functional Change and Efficacy of Duloxetine in Patients With Co-Morbid Depression & Soft Tissue Discomfort Syndrome
Status:
Completed
Trial end date:
2009-05-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to determine the time course of duloxetine efficacy on the
symptoms of Major Depressive Disorder (MDD)and on the symptoms of Soft Tissue Discomfort
Syndrome(STDS) via use of 24-hour Actigraph™ measures.
We hypothesize that there will be a reduction in both MDD and STDS symptoms in MDD patients
with co-morbid STDS symptoms. We further hypothesize that there will be a rapid improvement
in functional outcome ratings and 24-hour activity in MDD patients with co-morbid STDS
symptoms which may occur even before the antidepressant effect is observed.