Functional Applications of Hyperpolarized 129Xe MRI
Status:
Terminated
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
The overall objectives of our study are to determine the capabilities of hyperpolarized 129Xe
MRI to measure lung function and its potential to sensitively detect pulmonary disease and
its progression in COPD. We hypothesize that measurement of alveolar surface area, septal
thickness, and capillary transit time measured with hyperpolarized 129Xe will correlate
better with quality of life measures in COPD subjects than traditional diagnostic measures
such as spirometry and Computed Tomography.