Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2)
Status:
Completed
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to see if salsalate, an Nuclear factor-kappaB (NF-κB) mediated
inflammation inhibitor, or carvedilol, an α- and β-blocker, will protect against free fatty
acid induced hypertension, insulin resistance, endothelial dysfunction, inflammation and
oxidative stress, and autonomic dysfunction in obese normotensive subjects.