Fractional Laser Assisted Topical Anesthesia

• Status: Terminated
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess the efficacy of skin anesthesia using fractional laser assisted delivery of articaine hydrochloride 40 mg/ml and epinephrine 10 µg/ml solution (AHES) compared to standard anesthesia with topical eutectic mixture of lidocaine 25 mg/g and prilocaine 25 mg/g cream (EMLA cream) prior to ablative fractional laser treatment of acne scars and traumatic scars.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Netherlands Institute for Pigment Disorders
• Treatments: Anesthetics; Carticaine; EMLA; Epinephrine; Lidocaine; Lidocaine, Prilocaine Drug Combination; Prilocaine

Criteria

Inclusion Criteria:

• Patients with acne scars or traumatic scars scheduled for treatment with the fractional carbon dioxide laser

• Age ≥18 years

• Patient is willing and able to give written informed consent

Exclusion Criteria:

• Known allergy to local anesthesia

• Pregnancy or lactation

• Incompetency to understand what the procedure involves

• Current complaints of chronic pain or other alterations in pain sensation (e.g. due to diabetes mellitus or lepra)

• Current treatment with systemic analgesics or other medication that can influence pain sensation

• Total lesional area to be treated in one session >600 cm2