Overview

Fractional Laser Assisted Delivery of Anesthetics

Status:
Completed
Trial end date:
2014-10-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to assess the efficacy of fractional CO2 laser assisted delivery of topically applied anesthetics (articaine hydrochloride 40 mg/ml and epinephrine 10 μg/ml solution and EMLA cream) regarding to anesthesia of the skin.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Netherlands Institute for Pigment Disorders
Collaborator:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Treatments:
Anesthetics
Carticaine
EMLA
Epinephrine
Epinephryl borate
Lidocaine
Lidocaine, Prilocaine Drug Combination
Prilocaine
Racepinephrine
Criteria
Inclusion Criteria:

- Fitzpatrick skin type I or II

- Age ≥18 years

- Patient is willing and able to give written informed consent

Exclusion Criteria:

- History of keloid or hypertrophic scar formation or complicated wound healing

- Presence of any active skin disease

- Known allergy to local anesthesia

- Pregnancy or lactation

- Incompetency to understand what the procedure involves

- Current complaints of chronic pain or other alterations in pain sensation (e.g. due to
diabetes mellitus or lepra)

- Current treatment with systemic analgesics or other medication that can influence pain
sensation

- Current treatment with anticoagulants

- Fitzpatrick skin type III-VI

- Excessive sun tan