Fractional CO2 Laser Assisted Photodynamic Therapy

• Status: Completed
• Trial end date: 2012-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Nodular Basal Cell Carcinomas:

Compare the efficacy and safety of conventional versus fractional laser assisted PDT for difficult to treat nodular cell carcinomas in the face.

Actinic keratosis:

Compare the efficacy and safety of conventional versus fractional laser assisted PDT for moderate to severe actinic keratoses located in the face and on the hands.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bispebjerg Hospital
• Treatments: Aminolevulinic Acid; Methyl 5-aminolevulinate

Criteria

Inclusion Criteria:

• Age 18 or older

• Skin type I-III

• Fertile women using secure birth control

• Moderate to severe actinic keratoses in the face or on the hands,

• Difficult to treat nodular basal cell carcinomas in the face

Exclusion Criteria:

• Pregnancy or breast feeding patients

• Patients with porphyria

• Patients with Gorlins syndrome

• Patients with a tendency to produce hypertrophic scars or keloids

• Patients with known allergy to Metvix

• Patients who are not considered able to follow the treatment protocol (e.g. severely alcoholic, dementia, mentally ill etc.)

• Patients with pigmented or morphea basal cell carcinomas

• Know herpes simplex virus infection in treatment areas