Overview

Fortified Oral Rehydration Therapy for Pediatric Diarrhea

Status:
Recruiting
Trial end date:
2026-07-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to compare amino acid-fortified oral rehydration therapy (ORT) to the standard of care ORT in pediatric patients with acute gastroenteritis (AGE). The main questions it aims to answer are: - can amino acid-fortified ORT reduce the duration and severity of AGE compared to standard of care ORT? - can amino acid-fortified ORT increase the secretion of antimicrobial peptides in the gastrointestinal tract compared to standard of care ORT? Participants will be assigned to the experimental treatment (amino acid-fortified ORT) or the standard of care ORT and their disease severity, duration, and stool antimicrobial peptide content.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Paul A Breslin
Collaborator:
The Gerber Foundation