Food Reward in Native American Women

• Status: Active, not recruiting
• Trial end date: 0000-00-00
• Target enrollment: 75
• Participant gender: Female

Summary

This study aims to characterize the neurobiology of obesity in American Indians (AI) using functional MRIs to examine the correlation between brain response to food stimuli in AI women. A functional MRI (fMRI) is used to visualize brain activity when obese and lean AI women look at images of fattening food, non-fattening food and non-food objects. Additionally examined is the effect of the drug naltrexone to suppress brain response to visual food cues and calorie intake in the women.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Minnesota - Clinical and Translational Science Institute
• Treatments: Naltrexone
• Last Updated: 2016-06-08

Criteria

Inclusion Criteria:

• Female

• Self-identified AI

• BMI over 30 OR between 20 and 24.9

• Must see clearly with or without glasses

• Capable of giving informed consent

Exclusion Criteria:

• Smokes more than one cigarette a day

• Drinks more than two alcoholic drinks a day

• Uses recreational drugs

• Is pregnant

• Has had weight loss surgery

• Other major medical problems (e.g. diabetes)

• Taking medications that alter appetite or body weight

• Significant food allergies