Food Effect Study on Pharmacodynamic and Bioavailability of Clopidogrel 300/75 mg in Healthy Subjects
Status:
Completed
Trial end date:
2009-06-01
Target enrollment:
Participant gender:
Summary
Primary objective:
- Investigate the potential food effect on Adenosine diphosphate(ADP)-induced platelet
aggregation after 5-day repeated doses of clopidogrel (300 mg loading dose followed by 4
days 75 mg/day) in healthy subjects
Secondary objectives are to investigate the potential food effect on:
- ADP-induced platelet aggregation after 300 mg loading dose of clopidogrel
- Pharmacokinetic profiles of clopidogrel and its active metabolite after 5-day repeated
doses of clopidogrel