Follow-up and Steroid Treatment Results in Intussusception
Status:
Recruiting
Trial end date:
2027-12-24
Target enrollment:
Participant gender:
Summary
Treatment interventions in the treatment of intussusception are hydrostatic or pneumatic
reduction and manual reduction with laparotomy. In addition, it is known that in some of the
ileoileal intussusception cases, intussusception disappears in short-term observation and it
is an accepted treatment to follow-up for a while in ileoileal cases without making a
decision for laparotomy. In a study we conducted, we reported that 17 of 81 patients had
spontaneous opening with follow-up and no further treatment was required. The hydrostatic or
pneumatic reduction has a 0.8% risk of bowel perforation, fever due to bacterial
translocation is common, septicemia has also been reported and anal fissures due to
catheterization is seen. Baby or child's stress, psychology, abdominal pain are other
negative aspects that cannot be measured. Sonmez et al. reported that when a patient with HSP
was diagnosed with intussusception while under steroid treatment, and when they took the
patient to laparoscopy, they observed that the patient's intussusception was opened. In the
same study, Sönmez et al. mentioned that they followed up 4 patients diagnosed with HSP by
administering only steroid treatment and observed that intussusception was opened in 3 of
these patients without the need for any other intervention.
The steroid is used as a single dose (1 mg/kg) in cases such as acute allergic reactions,
bronchiolitis, asthma, laryngitis, edema treatment, bronchoscopy, intubation, extubation
medication. When the literature is reviewed, it has been shown that single-dose, low-amount
(1 mg/kg) steroid therapy does not have side effects. We predict that the steroid will reduce
the thickening of Peyer's plaques with its anti-inflammatory effect, and relieve edema as in
other areas of use, by relieving the congested intussusceptum. Thus, in infants and children,
there will be no need for hydrostatic or pneumatic reduction, which has the risk of
perforation and infection (septicemia) and exposure to radiation, and our patients will
regain their health without the need to apply this interventional treatment.