Statin therapy is a treatment with a proven positive impact on survival after heart
transplantation. However, it is unclear whether the beneficial effect of this class of drugs
depends solely on their LDL-lowering properties or on anti-inflammatory and immuno-modulatory
properties. Thus, this study was designed to compare safety and efficacy of two different
strategies: 1. high fixed statin dose vs. 2. low starting dose with LDL-driven doses
adjustments.