Fluoxetine to Reduce Cocaine Use in Cocaine and Opioid Addicts

• Status: Completed
• Trial end date: 2006-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Cocaine addiction is a serious health problem with no available medical treatment for preventing relapse. Fluoxetine, a medication that is currently used to treat depression and anxiety disorders, may also be effective at diminishing cocaine use in individuals with severe cocaine addiction. This study will evaluate the effectiveness of fluoxetine at reducing cocaine use in individuals addicted to cocaine and opioids who are concurrently receiving methadone treatment.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Cocaine; Fluoxetine

Criteria

Inclusion Criteria:

• Currently dependent on opioids

• Currently dependent on cocaine

• Eligible to receive methadone maintenance treatment

Exclusion Criteria:

• Current significant medical or psychiatric illness

• Current use of a specific serotonin reuptake inhibitor (SSRI)

• History of allergy to SSRI medications