Fluoxetine as a Quit Smoking Aid for Depression-Prone Smokers
Status:
Completed
Trial end date:
2005-01-01
Target enrollment:
Participant gender:
Summary
This project is a treatment-matching study to test whether adding antidepressant
pharmacotherapy to behavioral cessation treatment improves the depression-prone smoker's
ability to quit, while not undermining cessation goals for the smoker who lacks a history of
depression. The study target is to randomize 120 smokers with a prior history of depression
and 120 smokers who lack such a history to a double-blind treatment with either 60 mg
fluoxetine or placebo, while they undergo cognitive behavioral treatment to quit smoking.
Phase:
Phase 3
Details
Lead Sponsor:
US Department of Veterans Affairs VA Office of Research and Development