Fluorescence Imaging in Sentinel Lymph Node Biopsy for Breast Cancer and Melanoma
Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
The NIR light source of our device is based on light-emitting diodes (LEDs), which can
deliver sufficient light to biological tissues and induce fluorescence emission to meet the
needs of the planned clinical studies. It should be noted that the light source is still well
under the US FDA recommended limit for NIR exposure and ANSI standard. In addition, the light
source is not laser-based, which is significantly safer than other optical imaging systems
utilizing laser technologies. The fluorescence signals will be received by the detector
portion of our device. Gain-settings could be easily adjusted during operation to optimize
the contrast between high fluorescence areas (tumors) and low fluorescence areas (normal
tissues). Real-time fluorescence video will be displayed in the goggle eyepiece as well as on
a secondary monitor to facilitate viewing by other surgeons in the room.