Fludarabine or Observation in Treating Patients With Stage 0, Stage I, or Stage II Chronic Lymphocytic Leukemia
Status:
Completed
Trial end date:
2010-06-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as fludarabine, work in different ways to stop
the growth of cancer cells, either by killing the cells or by stopping them from dividing.
Sometimes, the cancer may not need treatment until it progresses. In this case, observation
may be sufficient. It is not yet known whether fludarabine is more effective than observation
in treating chronic lymphocytic leukemia.
PURPOSE: This randomized phase III trial is studying fludarabine to see how well it works
compared to observation only in treating patients with stage 0, stage I, or stage II B-cell
chronic lymphocytic leukemia.