Fludarabine With or Without Cyclophosphamide in Treating Patients With Advanced Chronic Lymphocytic Leukemia
Status:
Completed
Trial end date:
2007-07-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as fludarabine and cyclophosphamide, work in
different ways to stop the growth of cancer cells, either by killing the cells or by stopping
them from dividing. It is not yet known whether giving fludarabine together with
cyclophosphamide is more effective than fludarabine alone in treating chronic lymphocytic
leukemia.
PURPOSE: This randomized phase III trial is studying giving fludarabine together with
cyclophosphamide to see how well it works compared to fludarabine alone in treating patients
with advanced chronic lymphocytic leukemia.