Fludarabine / Total Body Irradiation Regimen for ALLO HCT in Acute Lymphoblastic Leukemia
Status:
Active, not recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The goal of this research is to test if the conditioning regimen, fludarabine and total body
irradiation (FluTBI), can lead to a safer and more effective stem cell transplant treatment
regimen for ALL patients older than 40 years of age and/or younger patients with high risk
medical conditions. The primary objective is to establish the efficacy of allo HCT in older
ALL patients using myeloablative FluTBI conditioning regimen. The investigators are also
assessing the safety and toxicity of allo HCT in older ALL patients using myeloablative
FluTBI conditioning regimen.