Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

• Status: Completed
• Trial end date: 2020-12-14

Summary

The goal of this clinical research study is to learn if combining busulfan with clofarabine and fludarabine can help control the disease better than the previous standard method (using busulfan and fludarabine alone) in patients with AML or MDS. The safety of this combination therapy will also be studied.

• Phase: Phase 3

Details

• Lead Sponsor: M.D. Anderson Cancer Center
• Collaborator: Sanofi
• Treatments: Antilymphocyte Serum; Busulfan; Clofarabine; Fludarabine; Fludarabine phosphate; Methotrexate; Tacrolimus; Thymoglobulin; Vidarabine