Overview

Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies

Status:
Recruiting
Trial end date:
2023-11-15
Target enrollment:
Participant gender:
Summary
This phase I trial studies the best dose and side effects of flotetuzumab for the treatment of patients with blood cancers (hematological malignancies) that have spread to other places in the body (advanced) and have come back after a period of improvement (relapsed) or does not respond to treatment (refractory). Flotetuzumab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread.
Phase:
Phase 1
Details
Lead Sponsor:
City of Hope Medical Center
Collaborator:
National Cancer Institute (NCI)
Treatments:
Acetaminophen
Antibodies
Antibodies, Bispecific
BB 1101
Dexamethasone
Dexamethasone acetate
Diphenhydramine
Ibuprofen
Ichthammol
Immunoglobulins
Promethazine
Ranitidine