Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 2

• Status: Completed
• Trial end date: 2019-02-25
• Target enrollment: 0
• Participant gender: All

Summary

This study is to examine if inhaled doses of an e-cigarette flavor, alone and in combination with menthol, changes the appeal of e-cigarettes containing low and high doses of nicotine. The hypothesis is that menthol and the other experimental flavor will interact with nicotine dose to improve taste and liking for e-cigarettes.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Yale University
• Treatments: Menthol; Nicotine

Criteria

Inclusion Criteria:

• Ages 18-20 years

• Able to read and write

• Urine cotinine levels of >250 ng/ml at screening appointment

• Use of e-cigarettes in the past month

• May or may not currently smoke traditional cigarettes

Exclusion Criteria:

• Seeking smoking cessation treatment

• Current/lifetime criteria for dependence on another psychoactive substance -Daily use of alcohol or marijuana or use of any other drugs including cocaine, opiates, stimulants

• Regular use of psychoactive drugs including anxiolytics, antidepressants and other psychostimulants

• Current or past history of psychosis or other psychiatric diagnosis such as major depression

• Any significant current medical condition