Fixed Versus Weight-Based Enoxaparin Dosing in Thoracic Surgery Patients

• Status: Completed
• Trial end date: 2019-07-27
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this research is to better understand how patient-level factors can be used to predict the appropriate enoxaparin dose to maximize venous thromboembolism (VTE) risk reduction and minimize bleeding.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Utah
• Collaborator: University of Michigan
• Treatments: Dalteparin; Enoxaparin; Enoxaparin sodium; Heparin, Low-Molecular-Weight

Criteria

Inclusion Criteria:

• receiving Video-Assisted Thoracoscopic Surgery

• able to have Enoxaparin initiated within 8 hours after procedure

Exclusion Criteria:

• Contraindication to use of enoxaparin

• Intracranial bleeding/stroke

• Hematoma or bleeding disorder

• Heparin-induced thrombocytopenia positive

• Creatinine clearance less than or equal to 30 mL/min

• Serum creatinine greater than 1.6 mg/dL

• Epidural catheter