Overview

Fixed Dose Rate Gemcitabine and Cisplatin Followed by Chemoradiation for Locally Advanced Pancreatic Cancer

Status:
Completed
Trial end date:
2011-06-01
Target enrollment:
0
Participant gender:
All
Summary
This is a phase Ⅱ trial of fixed dose rate gemcitabine and cisplatin chemotherapy followed by chemoradiation with capecitabine in patients with locally advanced pancreatic cancer.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Seoul National University Hospital
Treatments:
Capecitabine
Cisplatin
Gemcitabine
Criteria
Inclusion Criteria:

- unresectable locally advanced pancreatic cancer

- no distant metastasis

- histologically confirmed adenocarcinoma of pancreas

- 18-75 of age

- ECOG performance status 0-2

- normal marrow function :

- WBC at least 3,000/mm3 OR Absolute neutrophil count at least 1,500/mm3

- Platelet count at least 100,000/mm3

- normal liver function :

--Bilirubin no greater than 2.0 mg/dL AST less than 3 times upper limit of normal
(ULN)

- normal renal function :

--Creatinine no greater than 1.5 times ULN

- signed informed consent