Fish Oil vs. Placebo on Subjective Effects of Alcohol

• Status: Completed
• Trial end date: 2021-09-08
• Target enrollment: 0
• Participant gender: All

Summary

This project represents a first step in examining the potential use of fish oil for the treatment of alcohol use disorder (AUD). The investigators will be testing for attenuation of alcohol-induced sedative and stimulant effects, as well as cognitive effects and cerebellar effects in healthy social drinkers.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Yale University
• Collaborator: VA Connecticut Healthcare System
• Treatments: Ethanol

Criteria

Inclusion Criteria:

1. Male and females, between the ages of 21 and 55;

2. No current drug use disorder of any drugs of abuse (except tobacco or marijuana);

3. No current medical problems and normal ECG;

4. For women, not pregnant as determined by pregnancy screening nor breast feeding, and using acceptable birth control methods.

Exclusion Criteria:

1. Current major psychiatric illnesses including mood, psychotic, or anxiety disorders;

2. History of major medical illnesses; including liver diseases, heart disease, chronic pain or other medical conditions that the physician investigator deems contraindicated for the subject to be in the study;

3. Liver function tests (ALT or AST) greater than 3 times normal;

4. Allergy to seafood.