Fish Oil to Reduce Tobacco Use iN Expectant Mothers Study
Status:
Completed
Trial end date:
2018-09-05
Target enrollment:
Participant gender:
Summary
The purpose of this feasibility study is to obtain pilot data in preparation for an upcoming
R01 submission. The goals of that submission will be to conduct a clinical trial of n-3
LCPUFAs for smoking cessation in pregnant women. For this proposal, the investigators will
develop, test, and refine the recruitment strategy and collect data demonstrating the
investigators ability to successfully recruit pregnant women who are actively smoking. The
investigators will collect side effect, tolerability, and adherence data regarding the
intervention. Finally, the investigators hope to gather preliminary effect size data to allow
more formal estimates of sample size. The investigators hypothesize that pregnant smokers
randomized to n-3 LCPUFA supplementation will have higher smoking cessation rates and less
nicotine cravings compared to women allocated to placebo. The investigators intend to use
this preliminary data to inform a future randomized, double-blind, placebo-controlled trial
of n-3 LCPUFA supplementation for tobacco cessation.