Overview

First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2)

Status:
RECRUITING
Trial end date:
2027-12-31
Target enrollment:
Participant gender:
Summary
This is a Phase II, randomized, multicenter, open-label clinical trial designed to compare Disitamab Vedotin plus Sintilimab and S-1 with Trastuzumab plus chemotherapy Sintilimab for first-line treatment of HER2-Positive advanced gastric or gastroesophageal junction adenocarcinoma.
Phase:
PHASE2
Details
Lead Sponsor:
Qilu Hospital of Shandong University
Treatments:
Capecitabine
Cisplatin
disitamab vedotin
Fluorouracil
Oxaliplatin
S 1 (combination)
sintilimab
Trastuzumab