Overview First-in-human Dose Escalation and Expansion Study With the SIRPα-directed Monoclonal Antibody BYON4228 Status: Not yet recruiting Trial end date: 2025-12-01 Target enrollment: Participant gender: Summary This is the first-in-human study with BYON4228, a humanized monoclonal antibody (mAb) directed against SIRPα. Phase: Phase 1 Details Lead Sponsor: Byondis B.V.Treatments: Rituximab