Overview

First Strike, Second Strike Therapies for High Risk Metastatic Castration Sensitive Prostate Cancer

Status:
Recruiting
Trial end date:
2026-05-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research is to find if sequential therapy with combined androgen deprivation or hormonal therapy with luteinizing hormone release hormone (LHRH) analog plus a new hormonal agent (abiraterone, enzalutamide, or apalutamide) followed by chemohormonal therapy with docetaxel and LHRH analog would improve the outcome of high risk metastatic/stage IV prostate cancer.
Phase:
Phase 2
Details
Lead Sponsor:
H. Lee Moffitt Cancer Center and Research Institute
Collaborator:
BeiGene
Treatments:
Docetaxel
Hormones
Leuprolide
Prolactin Release-Inhibiting Factors
Relugolix
Triptorelin Pamoate