Finafloxacin for the Treatment of cUTI and/or Acute Pyelonephritis
Status:
Completed
Trial end date:
2015-10-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to evaluate the microbiological and clinical outcome
of treatment with finafloxacin for 5 days versus finafloxacin for 10 days versus
ciprofloxacin for 10 days as a reference comparator.
Finafloxacin shows increased activity in an acidic environment which is associated with
indications such as uUTI and cUTI. Given the acidic pH of urine and concentration of
finafloxacin excreted via the urinary tract in humans it should be proven if the finafloxacin
treatments offer significant advantages over the currently available treatments for UTI.