Fibrin Melanoma Axillary Node Study in Patients With Melanoma
Status:
Completed
Trial end date:
2020-04-09
Target enrollment:
Participant gender:
Summary
Primary Objective:
- To determine whether the use of a fibrin sealant applied to axillary soft tissues
following node dissection can result in earlier drain removal.
Secondary Objectives:
- To determine the postoperative morbidity rate using fibrin sealant following axillary
node dissection.
- To assess patient-valuation of outcome by performing a cost-benefit analysis using a
willingness-to-pay model.
- To determine if serum levels, lymphatic fluids level, or cutaneous expression of
vascular endothelial growth factor-D (VEGF-D), vascular endothelial growth factor-C
(VEGF-C) or their receptor, vascular endothelial growth factor receptor-3 (VEGFR-3)
correlates with nodal tumor burden or development of lymphedema in patients with
melanoma.