Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma
Status:
Not yet recruiting
Trial end date:
2025-05-31
Target enrollment:
Participant gender:
Summary
Normally, p53 helps prevent tumors from forming in the body. Early studies have shown that
Fenofibrate, a cholesterol-lowering drug, can restore normal function to p53 and can change
the metabolism of HPV-positive tumors in a way that stops the growth of tumors. The purpose
of this study is to understand how Fenofibrate can be used to treat HPV-positive cervical
cancers and cervical dysplasia. Researchers will examine collected tissue samples and
investigate various genes and proteins to see whether Fenofibrate has an effect on
HPV-positive cervical cancers and cervical dysplasia.