Overview

Feasibility of Conducting a Clinical Trial Assessing Efficacy of Lactate as Adjunctive Therapy in Patients With Major Depressive Disorder

Status:
Not yet recruiting

Trial end date:
2028-01-01

Target enrollment:

Participant gender:

Summary

The goal of this clinical trial is to test the efficacy of lactate (a natural substance) in combination with standard antidepressant treatment, in patients hospitalized for a major depressive episode. The main question[s] it aims to answer are: - does lactate diminishes depression severity when administered in combination with antidepressant ? - is it feasible to test lactate treatment in a large-scale clinical trial ? Participants will receive lactate intravenously daily (20 min infusion) for 5 days during hospitalisation (together with the standard antidepressant treatment). Researchers will compare with a group receiving a placebo instead of lactate to see if lactate has antidepressant effects.

Phase:

Phase 2

Details

Lead Sponsor:

Centre Hospitalier Universitaire Vaudois

Collaborator:

Fondation de Préfargier