Feasibility of Aggressive Albuminuria Reduction in Biopsy-Proven Diabetic Nephropathy - A Pilot Study
Status:
Recruiting
Trial end date:
2025-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this trial is to investigate the feasibility and safety of implementing a
protocol-based treatment aggressively targeting albuminuria in subjects with biopsy-proven
diabetic nephropathy and severely elevated albuminuria. If this approach is feasible, the
results of the trial will inform the design of a large-scale randomized clinical trial to
evaluate the effect of this treatment on hard kidney endpoints (initiation of dialysis,
kidney transplantation, and death from kidney failure) in subjects with biopsy-proven
diabetic nephropathy and severely elevated albuminuria.