Feasibility and Effectiveness of Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia
Status:
Recruiting
Trial end date:
2022-11-01
Target enrollment:
Participant gender:
Summary
This is a multi-center, phase 2A exploratory study of feasibility and effectiveness of
Inotuzumab Ozagomicin in adult patients with Acute Lymphoid Leukemia (ALL) with positive
minimal residual disease before any hematopoietic stem cell transplantation.
The study is divided in two cohorts; cohort 1 will enroll 38 Ph+ patients, cohort 2 will
enroll 38 Ph- patients, as defined with statistical analysis. The two cohorts will have the
same treatment, with the exception of short term and long term maintenance.