Feasibility Study of a Vaginal Ring for Delivery of TMC120 (Dapivirine)
Status:
Completed
Trial end date:
2005-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this trial was to evaluate the safety and feasibility of using a vaginal ring
to deliver the candidate microbicide TMC120 (dapivirine). Twelve women initially underwent
7-day exposure to a placebo ring containing no investigational agent. They then underwent
7-day exposure to a ring containing 120 mg of TMC120 (dapivirine). Feasibility was assessed
in terms of safety and tolerability as well as drug delivery.