Overview

Feasibility Study of Intraperitoneal Paclitaxel

Status:
Unknown status
Trial end date:
2018-08-01
Target enrollment:
Participant gender:
Summary
This is a single arm phase 2 trial evaluating the efficacy and tolerability of intraperitoneal paclitaxel with oxaliplatin and capecitabine in advanced gastric cancer patients with peritoneal metastasis and/or cancer cells on peritoneal cytology. Twenty patients will be recruited into the study for an estimated period of two years. Paclitaxel will be administered intraperitoneally at 40mg/m2 on Day 1 and 8 in patients receiving standard intravenous oxaliplatin 130mg/m2 on Day 1 and capecitabine 1000mg/m2 on day 1-14. The study hypothesizes that the addition of intraperitoneal paclitaxel with chemotherapy will improve treatment efficacy.
Phase:
Phase 2
Details
Lead Sponsor:
National University Hospital, Singapore
Treatments:
Albumin-Bound Paclitaxel
Capecitabine
Oxaliplatin
Paclitaxel