Overview

Fatty Acid Oxidation Defects and Insulin Sensitivity

Status:
Completed
Trial end date:
2021-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to learn more about what causes insulin resistance. It has been suggested that proper breakdown of fat into energy (oxidation) in the body is important to allow insulin to keep blood sugar in the normal range. The investigators want to know if having one of the fatty acid oxidation disorders could have an influence on insulin action. Fatty acid oxidation disorders are genetic disorders that inhibit one of the enzymes that converts fat into energy. The investigators will study both normal healthy people and people with a long-chain fatty acid oxidation disorder.
Phase:
N/A
Details
Lead Sponsor:
Oregon Health and Science University
Treatments:
Calcium heparin
Glycerol
Heparin
Insulin
Soybean oil, phospholipid emulsion