Family History Study of Alcohol Consumption Using Memantine
Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the effects of the study medication, memantine
(placebo, 20 mg or 40 mg/day) on alcohol drinking behavior in a laboratory setting in which
participants are given an initial drink of alcohol followed by the choice to drink up to 12
more drinks over a three-hour period. We hypothesize that memantine will reduce craving and
number of drinks consumed prior to and after exposure to the initial drink of alcohol and
during the three hour drinking period. We will also evaluate the influence of family history
of alcoholism on the efficacy of memantine in reducing alcohol drinking behavior.
Phase:
Phase 2
Details
Lead Sponsor:
Yale University
Collaborator:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)