Familial Atherosclerosis Treatment Study

• Status: Completed
• Trial end date: 1989-08-01
• Target enrollment: 0
• Participant gender: Male

Summary

To compare the effects of two intensive lipid-lowering regimens with conventional therapy on coronary atherosclerosis as assessed by arteriography.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Washington
• Collaborator: National Heart, Lung, and Blood Institute (NHLBI)
• Treatments: Colestipol; Dihydromevinolin; L 647318; Lovastatin; Niacin; Niacinamide; Nicotinic Acids

Criteria

Inclusion Criteria:

• Men

• Age 62 or younger

• elevated apolipoprotein B levels

• coronary atherosclerosis

• family history of coronary heart disease.

Exclusion Criteria:

• diabetes

• severe hypertension

• cancer

• liver disease

• thyroid disease

• kidney disease