Factors Affecting the Effective End-tidal Concentration of Desflurane Anaesthesia

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

There is accumulating evidence that inappropriate depth of anaesthesia is associated with increased risk of postoperative complications including risk of death. The aim of this study was to identify factors determining the effective end-tidal concentration (EEtC) of desflurane, duration of wash in and wash out phase, and to estimate the risk of perioperative awareness in patients undergoing elective neurosurgical procedure.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Hradec Kralove
• Treatments: Anesthetics; Desflurane; Isoflurane; Nitric Oxide

Criteria

Inclusion Criteria:

• ASA I-III

• elective neurosurgical procedure under general anaesthesia

• Age between 18 and 78

• elective procedures with estimated duration 1 - 3 hours

Exclusion Criteria:

• Glasgow coma scale GCS below 14

• other rhythm than sinus

• pacemaker stimulation

• planned postoperative ventilation