Factors Affecting Methamphetamine and Opiates Drug Testing
Status:
Completed
Trial end date:
2014-01-31
Target enrollment:
Participant gender:
Summary
Background:
- Some legal over-the-counter drugs (such as Vicks VapoInhaler ) and some foods (such as
poppy seeds) may cause a positive screening drug test. This might look like someone used
illegal drugs (such as methamphetamines or opiates) when they did not. Researchers are
studying how the body handles chemicals that may test like illegal drugs and for how long
they may be detected in the body. Blood, saliva, and urine samples will be collected. This
study may help improve the effectiveness and accuracy of drug tests.
Objectives:
- To see how the body handles chemicals that may produce positive screening tests and how
additional testing can eliminate positive drug tests from over-the-counter drugs and food.
Eligibility:
- Healthy volunteers between 18 and 65 years of age.
Design:
- Participants are screened with a physical exam, medical history, laboratory tests, and
ECG.
- This study involves an overnight stay on a secure research unit and 2 days of tests.
- On the first day, participants will take Vicks VapoInhaler (two inhalations in each
nostril) every 2 hours from 9 a.m. to 7 p.m. They will also take a drink containing
poppy seeds twice (at about 9 a.m. and 5 p.m.).
- On the morning of the second day, participants will take the Vicks VapoInhaler just
once. They will be discharged around 5 p.m.
- On both days, participants will provide blood and saliva samples several times
throughout the day. All of their urine will be collected during the 2 study days....