Overview

FTT PET/CT in Pancreatic Neuroendocrine Tumors

Status:
NOT_YET_RECRUITING
Trial end date:
2027-09-01
Target enrollment:
Participant gender:
Summary
A pilot study to evaluate the expression of PARP-1 in patients with pancreatic neuroendocrine tumors will be conducted. This will be done via the use of a novel PET imaging agent, \[18F\]FluorThanatrace (\[18F\]FTT). A total of 12 patients will be enrolled. Patients will undergo a study imaging assessment using a whole-body PET CT scanner. Dynamic images will be obtained beginning immediately prior to the administration of 10 mCi of \[18F\]FTT (20%) for a total of 60 minutes. A static scan at 90 minutes post injection will subsequently be obtained. \[18F\]FTT uptake will be measured on the PET scan and correlated with two molecular outcomes.
Phase:
PHASE1
Details
Lead Sponsor:
Abramson Cancer Center at Penn Medicine
Collaborator:
University of Pennsylvania